10:56pm: Shanahan announced that Purdy will start this week.
11:54am: Further signs point toward Week 11 being the point at which Brock Purdy will return to action. The 49ers’ upcoming practice days will be key, but the team’s starting quarterback could be back in the fold on Sunday. 
Purdy did not dress for Week 10, but head coach Kyle Shanahan said he could have suited up as the team’s backup for that game. As such, many have expected San Francisco’s game against Arizona will be the point at which Purdy reclaims his starting quarterback role. In his latest comments on the matter, Shanahan said (via Cam Inman of the San Jose Mercury News) the 49ers anticipate having their QB depth chart back to full strength if things go according to plan over the next few days.
Mac Jones has performed admirably in Purdy’s absence, leading some to wonder about the 49ers preferring to continue with him under center the rest of the way. Especially given the fact the team does not foresee Purdy’s turf toe healing in full by the end of the campaign, an especially cautious approach would be feasible. Nevertheless, a strong showing in practice will set Purdy up for a return. Ian Rapoport of NFL Network adds (video link) the Iowa State product’s participation this week has been “much more intense” than in previous weeks.
“We’re seeing how the week goes,” general manager John Lynch said of the situation during his latest KNBR radio appearance (via Matt Maiocco of NBC Sports Bay Area). “If he shows his health and his ability to perform at a level we know Brock can play at, then he’ll be out there.”
The 49ers sit at 6-4 on the year and their playoff fate will be heavily influenced by the ability of several key players to return to health in the near future. In Purdy’s case, avoiding another reaggravation of his injury will be imperative given the massive financial commitment made by the team this past spring. The 25-year-old inked a five-year, $265MM extension ensuring his status as San Francisco’s franchise passer for the foreseeable future.
Jones has delivered consistent performances during his time atop the depth chart. In spite of that, the 49ers have remained adamant Purdy will operate as the starter once he returns to the lineup. Barring something unforeseen, that will very likely take place this weekend.

Schrödinger’s QB Health Status. We shalln’t know if Brock Purdy is healthy or not until we see who starts at QB for the 49ers on Sunday.
That’s PURDY good news.
Great, rush Purdy back into the starter’s role. Such a precipitous return to action ensures Mac Jones is almost certain to start half the remaining 49er games for this season and next. Two years is the duration of his contract.
I hardly think you can call the approach to Purdy’s injury “rushed”
Watch Purdy get re-injured this week or next, Druuuu. Turf-toe: defensive linemen probably know about it and the more aggressive ones might just accidentally run into Purdy’s feet during a QB pressure. Sean Payton specialised in these kind of bounty kills.
QBs basically wear the red jersey during actual games. I agree a toe injury to a QB with Purdys below average arm strength can be a problem, but I assume that’s what the delay has been week in and week out for him. if he possessed elite arm strength he would have already played, but Purdy needs every function of his body to be healthy to generate a passable amount of arm strength to survive in the NFL week in and week out. He’s an amazing decision maker when throwing the ball, truly elite, but his raw arm talent is what holds him back. If anything isn’t right healthwise, he can’t play because he needs to be healthy to have enough to physically get the ball where he wants. His brain know the right play almost every throw, just a question of if his body can get it where he wants.
One good season and then hurt almost every other time.
The 49ers offense is completely one dimensional. They have no run game. Luckily for them, the Cardinals defense ranks 27th in sack percentage so there’s a chance Purdy might avoid further injury.
I love Purdy, but this makes zero sense. Every doctor not on the 49ers training staff says it takes 6 weeks of doing NOTHING to have a CHANCE at coming back from turf toe. Mac is playing great. Why the rush? No trades at deadline tell me ShanaLynch don’t value this season
The 49ers staff doctors don’t have to pay Purdy that $265MM…lol.
The 49ers have to pay that salary for the next three years, whether they like it or not. Chronic turf toe would lose the 49ers a lot more money than sitting Purdy a few more games. Presumably the 49ers want Purdy for the playoffs.