49ers Place Isaiah Prince On IR, Make Five Other Moves

The 49ers made six roster moves on Monday, per a team announcement, including the placement of veteran offensive tackle Isaiah Prince on season-ending injured reserve.

Prince, 28, was auditioning for a depth tackle job in San Francisco before suffering a left knee injury on Saturday against the Chargers, per Matt Barrows of The Athletic. Originally a Dolphins sixth-round pick in 2019, Prince has also played for the Bengals, Falcons, and Titans in his career with 22 appearances and six starts. The 28-year-old will now spend the season on the IR unless he pursues an injury settlement.

The 49ers also released veteran running back Ke’Shawn Vaughn a few days after acquiring Brian Robinson from the Commanders. Vaughn spent the 2024 season on San Francisco’s practice squad and played a handful of snaps across three appearances, primarily on special teams. He began his career as a Buccaneers third-round pick in 2020 and played a tertiary role in their backfield over his first four seasons.

Here are the team’s four other moves:

Waived/injured:

Waived:

Bradley and Mordecai, a pair of 2024 UDFAs, appeared to pick up injuries on Saturday, according to Barrows. They will revert to the 49ers’ IR if they go unclaimed before Wednesday’s waiver deadline. As a result, veteran Nate Sudfeld will likely be the team’s third quarterback, though San Francisco may want to release him during final roster cuts and bring him back on the practice squad.

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