Brock Purdy Suffered Setback With Turf Toe Injury, Could Miss Week 6

By Ben Levine | at October 3, 2025 10:45 am

OCTOBER 3: Shanahan confirmed (via Cam Inman of the Bay Area Sports Group) that Purdy re-aggravated his injury and will again be week-to-week moving forward.

“[I] don’t know how it will heal,” added Shanahan.

The 49ers can be patient with Purdy’s recovery, as Jones has played well in his three starts, including a 342-yard, two-touchdown perfomance on Thursday night against the Rams. However, the team’s financial commitment to Purdy will likely stave off any chance of a quarterback controversy. Instead, Jones could follow in Sam Darnold‘s footsteps and parlay his success in San Francisco into a starting gig elsewhere.

OCTOBER 2: While it sounded like a short turnaround was the main reason for Brock Purdy‘s absence from tonight’s Week 5 contest, the 49ers QB may actually be sidelined for more than just this week. According to NFL Network’s Ian Rapoport, Purdy suffered a setback with his turf toe injury and is now considered week-to-week.

Per Rapoport, the quarterback reported soreness following his return in Week 4. The player later underwent an MRI, which revealed an aggravation of his lingering injury. As a result, Purdy is now at risk of missing more than just Week 5, with Rapoport hinting that the 25-year-old could also sit out the 49ers’ Week 6 matchup against the Buccaneers.

Purdy missed Weeks 2 and 3 while dealing with the turf toe injury. He returned for Week 4 and didn’t miss a snap, but he informed coach Kyle Shanahan of some soreness following the loss. Shanahan noted that Purdy and the team had to navigate “a totally different element” considering the four-day turnaround before Thursday Night Football, and after being listed as a non-participant on Monday, the quarterback was later ruled out for Week 5.

Now, it sounds like Purdy is at risk of missing at least his fourth game of the 2025 campaign. The former Mr. Irrelevant has generally stayed healthy throughout his career. He suffered a torn UCL as a rookie during the NFC Championship Game but managed to return for 16 games as a sophomore. He also missed a pair of games in 2024 thanks to shoulder and elbow injuries.

In two games this season, Purdy has completed 65.8 percent of his passes for 586 yards, four touchdowns, and four interceptions. After tossing 31 touchdowns as a sophomore, Purdy finished the 2023 campaign with 20 touchdown passes. The QB inked a five-year, $265MM extension with the 49ers back in May.

Mac Jones will continue to start for the 49ers as long as Purdy is sidelined. The former first-round pick has guided the 49ers to a pair of wins through his first two starts, tossing four touchdowns vs. only one interception.