The Chargers have agreed to a deal with first-round edge defender Akheem Mesidor, Adam Schefter of ESPN reports. As the 22nd overall pick, Mesidor inked a four-year, $20.46MM contract.
Despite his age (25) and past injury issues, Mesidor was widely expected to come off the board in the first round. He was one of the top 30 prospects available, according to both Daniel Jeremiah of NFL.com (No. 26) and Dane Brugler of The Athletic (No. 28). The Buccaneers reportedly would have taken Mesidor 15th overall had former Miami teammate and fellow edge defender Rueben Bain Jr. not slid to them.
Mesidor is entering the NFL with plenty of experience, having played in 65 college games over six seasons. The Canada native began at West Virginia, where he tallied 70 tackles, 14.5 TFL and 14.5 sacks from 2020-21.
Mesidor was mostly an interior lineman with the Mountaineers, but he took on an edge role upon transferring to Miami in 2022. After racking up 10.5 TFL and seven sacks in 11 games in his first season with the Hurricanes, foot problems held Mesidor to three appearances in 2023. He stayed healthy in his final two seasons at Miami, though, and his production exploded during a 15-game 2025. The 6-foot-3, 259-pounder amassed 38 tackles, 17.5 TFL and 12.5 sacks en route to first-team All-ACC and second-team All-America honors.
As someone who is also a capable run defender, Mesidor projects as a three-down player in the pros, according to Brugler. He could begin his career as the third or fourth option in a talented group of edge defenders in Los Angeles.
The Chargers lost Odafe Oweh to the Commanders’ four-year, $100MM offer in free agency, but they still boast Khalil Mack and Tuli Tuipulotu as starters. Bud Dupree and Kyle Kennard are in the mix as depth. Kennard is the only member of that quartet signed past the upcoming season, but the 2025 fourth-round pick disappointed during a five-game, two-tackle rookie campaign. The Chargers will expect much better production from Mesidor during his first season. If he pans out and the Chargers extend Tuipulotu, which general manager Joe Hortiz hopes to do, they will have a formidable pass-rushing duo for the next several years.
With Mesidor under wraps, the Chargers have locked up seven rookies from an eight-player class. Fourth-round receiver Brenen Thompson is the last unsigned pick standing.