Knee surgery has left T.J. Sanders unavailable since he last played in Week 4. The second-round rookie is set to return to action tomorrow, however. 
Sanders was activated from injured reserve on Saturday, per a Bills announcement. The move comes as no surprise since his practice window was opened earlier this week. Buffalo now has five IR activations remaining for the regular season.
Injuries along the defensive front have been an issue in 2025 for the Bills. Ed Oliver‘s biceps tear will keep him sidelined for the foreseeable future, while Michael Hoecht suffered an Achilles tear during just his second appearance of the campaign. Most recently, Landon Jackson has landed on IR and his availability regarding a return late in the year is in question.
Buffalo has allowed an average of nearly 148 yards per game on the ground this season, which ranks 30th in the league. Reinforcements along the defensive interior will be key as the team looks to make needed improvements in that regard. Sanders logged a 49% snap share prior to suffering his injury, and a notable workload should be expected once again as he returns to the lineup.
In other roster news, the Bills have signed Mecole Hardman from the practice squad to the active roster. The veteran wideout recently joined the team via a taxi squad pact and he will see playing time in short order. Hardman will not be expected to handle much in the way of offensive snaps early in his Buffalo tenure, but he could see usage in the return game right away. To make room for him on the roster, Brandon Codrington was waived.
Gabe Davis is also set to make his season debut tomorrow. The veteran receiver returned to Buffalo just before the start of the season before spending a lengthy period on the practice squad IR list. Davis is now healthy and with the team struggling for production at the WR spot, he will look to carve out at least a rotational role as a familiar Josh Allen target.
Dalton Kincaid will not play against the Buccaneers on Sunday. Depth at that position will come in the form of Keleki Latu, who joins Davis as a gameday elevation from the practice squad. Latu will make his NFL debut if he dresses tomorrow.