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Brandon Aiyuk

Mac Jones To Start Week 10; Latest On Other 49ers Injuries

November 7th, 2025 at 7:53pm CST by Ely Allen

Every week, there seems to be something injury-related coming out of the Bay Area. Whether it’s somebody preparing to miss a lot of time, a “will he” or “won’t he” gametime decision, or questions on timetables for return, the 49ers have provided headlines all season. The latest such headline pertains to the middle option as a questionable Brock Purdy will watch Mac Jones start for the sixth week in a row, per Tom Pelissero of NFL Network.

It’s become a weekly post with Purdy, who has been on the team’s injury report every week since he was hurt in the season opener. The 25-year-old has been getting closer and closer to coming back, and head coach Kyle Shanahan communicated that he could still be active as a backup to Jones. Third-string passer Adrian Martinez was signed from the practice squad to the active roster back in October as Purdy was nearing a return back then, so with three quarterbacks on the 53-man, Purdy could either be a primary backup or an emergency third option.

The quarterback role we do know, though, will be Jones, who will start under center for the eighth time this year. After winning his first three starts as an injury replacement, Jones has cooled off, alternating losses and wins since then. Despite a largely injured supporting cast around him, Jones is averaging a career-high 261.7 passing yards per game while also sporting the best touchdown:interception ratio (10:5) of his career. He’ll be looking to buck the trend of alternating finishes after beating the Giants last week.

One player we know won’t be out there is wide receiver Ricky Pearsall. The second-year pass-catcher has been missing since Week 4 and is about to miss his sixth game in a row. Asked about what’s holding Pearsall from being able to play, Shanahan told the media that “he hasn’t been able to hit his normal speeds that would allow him to come back,” per Cam Inman of the Bay Area News Group. Reporters noted the young wideout had been sighted doing sprints at practices and shooting jump shots in the locker room, but Shanahan was adamant that the team is waiting for Pearsall to be able to hit his old marks.

Pearsall isn’t the only receiver unavailable this week. Veteran wideout Brandon Aiyuk remains on the reserve/PUP list ten weeks into the season. November was offered up last month as a potential return window for the 27-year-old receiver. It’s now been over a year since Aiyuk has appeared in a game, and each week, expectations for Aiyuk’s 21-day practice window to be opened go unrealized. Shanahan continues to seem vaguely optimistic, with Vic Tafur of The Athletic quoting him as “pretty confident” that Aiyuk will be back sometime this season.

Given the extended absences of players like Purdy and Pearsall, among some others, there have been questions on why players missing so much time weren’t put on injured reserve. According to The Athletic’s Matt Barrows, the primary reason is simply that they didn’t expect each player to be out for so long. Additionally, while the NFL has implemented the current system wherein teams can bring players back from IR, each team is only given eight such activations.

Lucky teams can put players with minor injuries on IR and activate them four weeks later just to manipulate roster numbers. With so many injuries week in and week out, the 49ers likely would’ve loved to place guys on IR so they could add healthy reinforcements to the roster. Knowing how many impact players they had already placed on IR, though, San Francisco needed to be weary of how it would be able to utilize its limited activations.

One player that did land on IR recently was edge rusher Yetur Gross-Matos. Gross-Matos had been out since Week 5 and was expected to make a return soon. Unfortunately, the 27-year-old defender strained his hamstring again near the end of last week, per ESPN’s Nick Wagoner. While it will take Gross-Matos some time to work his way back from the injury, Shanahan doesn’t believe he will be sidelined for the remainder of the season.

49ers’ Brandon Aiyuk Will Not Practice This Week; Ben Bartch’s Practice Window To Open

October 28th, 2025 at 9:48am CST by Adam La Rose

Injuries to key players remain an issue at many positions for the 49ers. Preparation for Week 9 will bring about a mixed bag of updates on that front.

Brandon Aiyuk continues to rehab the ACL and MCL tears which ended his 2024 campaign. While progress is being made in his recovery, San Francisco’s top wideout will not take part in practice this week. That decision will further delay the point at which Aiyuk’s 21-day activation window will be opened.

“I think it’s week-to-week from here on out that he has got a chance,” head coach Kyle Shanahan said of Aiyuk (via Matt Maiocco of NBC Sports Area). “It would’ve surprised me if it was this week, but that was just me saying that every week I think he’s getting closer to having a chance. Just not this week.”

Shanahan recently opened the door to Aiyuk suiting up for practice this week, but that will not take place. A return in November is instead still the goal in this case. Provided the 27-year-old can return to full strength relatively soon, his presence will be welcomed on a 49ers offense which has dealt with injuries under center and at the skill positions all season. Along the offensive line, meanwhile, a notable return is imminent.

The 49ers will designate left guard Ben Bartch for return this week, as noted by The Athletic’s Matt Barrows. Bartch has been on injured reserve since mid-September due to a high ankle sprain. Beginning tomorrow, though, his practice window will open. That will leave the 49ers with three weeks to activate Bartch.

The former fourth-rounder has started just four of his appearances with the 49ers, but that total will likely increase once Bartch is activated. He opened the season as San Francisco’s starter at the LG spot vacated by Aaron Banks‘ free agent departure. Provided that remains the case moving forward, Bartch will be counted on to provide stability along the interior of the offensive line. As a pending free agent, his play upon being activated will be key in determining not only the 49ers’ success up front but also his earning potential on the open market next spring.

The 49ers have used two of their eight IR activations for the season so far. Bringing Bartch back into the fold will lower that figure, with the same being true when fellow O-linemen Spencer Burford is activated (which should take place in the near future). Aiyuk resides on the reserve/PUP list, so his return will not count toward the IR activation count; when it will take place nevertheless remains something to monitor closely for the 49ers.

49ers Rumors: DE Trade, Warner, Aiyuk, Bosa

October 26th, 2025 at 11:37am CST by Rory Parks

Despite another barrage of injuries to marquee players, the 49ers are 5-2 and in a three-way tie for first place in the NFC West. Following the season-ending ACL tear that standout pass rusher Nick Bosa sustained in Week 3, GM John Lynch said the club would look to the trade market for reinforcements on the edge (comments he seemed to walk back to an extent in the wake of the potentially season-ending ankle injury that star linebacker Fred Warner suffered in Week 6). 

Now, offseason trade acquisition Bryce Huff – whose role had increased with Bosa on the sidelines – is set to miss some time due to a hamstring ailment. Notwithstanding the remarks he made after the Warner injury, Lynch is surely doing his due diligence on EDGE players who might be available via trade, and he conceded he will pull the trigger if the right opportunity presents itself. That has not happened yet, but it could.

When asked about the possibility of adding a defensive end, Lynch told KNBR radio, “[w]e don’t have to … But we have plenty in this building … We’ll hold down the fort until [Huff’s hamstring is healed]. If it can help our team we won’t hesitate to do it. But nothing has presented itself that aligns completely to this point” (via Cam Inman of the San Jose Mercury News). 

The trade deadline is a little more than a week away, and talks around the league will surely heat up as November 4 draws nearer. ESPN’s Jeremy Fowler noted that teams with pass rushers to deal are (understandably) seeking significant compensation in return for their premium-position talent. Prospective buyers, meanwhile, are hoping the price will come down in the upcoming days, leading Fowler to believe the EDGE market could be a late-forming one. 

As Lynch continues to survey that market, he could soon get some much-needed good news on the injury front. After a disappointing September update on wide receiver Brandon Aiyuk’s ACL and MCL tears – which he suffered in Week 7 of the 2024 campaign – recent reports suggested the club was targeting a November return for the 2020 first-rounder. It still seems that is the case, as head coach Kyle Shanahan recently told reporters (including ESPN’s Nick Wagoner) that Aiyuk could begin practicing as early as this week. Whenever San Francisco opens Aiyuk’s practice window, it will have up to 21 days to activate him. Failing that, he will revert to season-ending injured reserve.

Surgeons whom Matt Barrows of The Athletic consulted said Warner could be healthy enough to return for the playoffs should the Niners qualify, and Lynch confirmed as much. Per Eric Branch of the San Francisco Chronicle, the GM did not rule out the possibility of a postseason return for Warner.

Bosa, on the other hand, is definitely done for the rest of the regular season and any potential postseason contests. Wagoner reported at the end of September that Bosa’s surgery on his torn ACL went well, and Barrows said the Niners could see up to $9MM in cap savings as a result of the insurance policy they took out on Bosa’s mega-deal.

49ers’ George Kittle Has Chance At Week 7 Return; November Reemergence Targeted For Brandon Aiyuk

October 14th, 2025 at 2:51pm CST by Sam Robinson

Once again battered by injuries, the 49ers have still managed to reach 4-2 despite a spree of setbacks for the second straight season. Pro Bowlers Brock Purdy, George Kittle and Nick Bosa have missed time, and the Fred Warner loss deals a blow the team has not previously encountered.

On the team amid the 2020 and 2024 injury waves, Warner has missed one career game. The All-Pro linebacker has crafted a Hall of Fame-caliber resume during the 49ers’ Kyle Shanahan-era surge, but he will undergo surgery Wednesday and joins Bosa in being out for the season. The 49ers are eyeing trades on defense, but their offense is starting to look healthier (even if Jauan Jennings is playing through a significant rib injury).

[RELATED: 49ers Expected To Inquire On Trey Hendrickson Trade]

While Purdy’s status remains murky, Kittle is nearing a return. Shanahan does expect (via 49ers reporter Briana Jeannel) the All-Pro tight end will be designated for return from IR ahead of the Falcons matchup. This would allow the 49ers a ramp-up period, but Shanahan added (via NBC Sports Bay Area’s Matt Maiocco) the hope is Kittle returns for Week 7.

Although the 49ers’ injury trouble is again mounting, they are not in bad shape yet in terms of IR activations. The team has either seen key players suffer season-ending injuries (Bosa, Warner) or remain on the active roster in week-to-week setups (Purdy, Jennings, Ricky Pearsall). The 49ers did place starting guard Ben Bartch on IR, and he is eligible for activation this week. It is uncertain if Bartch will join Kittle in being designated for return.

Kittle went down with a hamstring injury in Week 1. The likely Hall of Fame-bound pass catcher suited up for 15 games last season and did not miss any time due to injury in 2023. Playing in at least 14 games in 2021 and ’22, Kittle has not missed this much time in a season since being part of the 49ers’ spate of maladies in 2020. He missed eight games that season, suffering a sprained knee and fractured foot during San Francisco’s 6-10 season.

With Pearsall on the active roster, the 49ers are moving closer to full strength after seeing both their top two receivers go down early this season. San Francisco’s true No. 1 receiver, however, remains on the reserve/PUP list. Brandon Aiyuk‘s timetable has been pushed back a bit. Week 6 was floated months ago as a loose return window, but that has come and gone. Shanahan has now mentioned Week 10 as an updated window (via Maiocco) but stopped short of providing a firm timetable.

Out since October 20, 2024 with an ACL tear, Aiyuk has been in rehab mode after the tear was not deemed clean. Joining Kittle in suffering an injury shortly after an offseason extension, Aiyuk has been unable to build on the second-team All-Pro season he produced in 2023. John Lynch said in late September the sixth-year veteran was “not close” returning, but Shanahan’s update does provide a semi-positive sign a reemergence near the midseason point is still in play.

Like the IR-return process, the 49ers would have a 21-day period to observe Aiyuk in practice before activating him. Given the length of Aiyuk’s rehab process, it would surprise if he suited up the week he was designated for return. It should be expected, based on this timeline, Aiyuk would be in the PUP-return window soon. But the 49ers will continue to make do with a ravaged receiver depth chart for the time being. Though, Kittle’s return will help the passing attack considerably while Aiyuk hits the recovery homestretch.

John Lynch: 49ers WR Brandon Aiyuk ‘Not Close’ To Return

September 25th, 2025 at 1:40pm CST by Nikhil Mehta

49ers general manager John Lynch said that wide receiver Brandon Aiyuk is “not close” to returning to the field from last year’s devastating knee injury.

“There’s no absolutes on these things,” said Lynch on Wednesday (via KNBR). “He’s gotta continue to hit markers. He’s tracking well, we’ll be a better team when Brandon’s out there.”

Aiyuk tore his ACL and MCL in Week 7 last year, setting him up for a lengthy recovery process that will extend well into this season. In August, Lynch said that there was no timetable for Aiyuk’s return, while head coach Kyle Shanahan suggested that the veteran wideout could return around Week 6.

Aiyuk started the season on the physically unable to perform list, making him ineligible to practice until next week. He would then have three weeks to be activated to the 53-man roster or revert to season-ending injured reserve, a situation the 49ers will want to avoid. Lynch’s comments further indicate that Aiyuk won’t be back anytime soon, though the veteran receiver was seen working out during a practice last week, per CBS Sports’ Matt Lively.

As a result, San Francisco will continue to work with a thin receiving corps until Aiyuk’s return, as the team has dealt with injuries to Jauan Jennings (ankle, shoulder) and Ricky Pearsall (knee) this year as well. Rookie Jordan Watkins is dealing with a calf injury, but has avoided injured reserve for the time being despite some early prognostications of an extended absence. All three wideouts were absent on Wednesday, though Pearsall said (via KNBR) that he would play “if there was a game today.” Jennings missed every practice last week and didn’t play on Sunday, though the 49ers will certainly be hoping he’s ready to go for Week 4.

Pearsall has impressed amid his teammates’ absences this year, racking up 281 yards in 16 catches through three games. Jennings has 105 yards in his two starts, while Kendrick Bourne has added 70 yards in the last two games. If their WR health issues continue, the 49ers will need Skyy Moore and Marquez Valdes-Scantling to step up for their next few games.

49ers Cut 25 Players, Set 53-Man Roster

August 26th, 2025 at 5:45pm CST by Ben Levine

The 49ers had some work to do to get down to their initial 53-man roster. The front office achieved that daunting task this afternoon, as the organization announced the following moves:

Released:

Waived:

Activated from active/PUP:

Placed on reserve/PUP:

Placed on reserve/NFI:

Placed on reserve/suspended:

Placed on IR (designated for return):

Placed on IR:

Punter Thomas Morstead was cut today, but it sounds like the veteran won’t be a free agent for long. Matt Barrows of The Athletic reports that Morstead is expected to re-sign with the organization. The 39-year-old spent the past two seasons with the Jets, including a 2023 campaign where he led the NFL in punts and punting yards.

Barrows also notes that Jacob Cowing made the initial roster but is expected to land on injured reserve as he nurses a hamstring injury. This could open the door for one of the team’s cut WRs to land back on the active roster. That grouping includes Russell Gage, who had more than 1,500 receiving yards for the Falcons between the 2020 and 2021 seasons.

Elsewhere on offense, Jeff Wilson‘s reunion with the 49ers proved to be short lived after he joined the organization earlier this month. The veteran spent the past two-plus seasons in Miami, but he had a successful run in San Francisco to begin his career. This included a 2020 campaign where he compiled 733 yards from scrimmage and 10 touchdowns.

Kyle Shanahan Targeting Week 6 Return For Brandon Aiyuk

August 11th, 2025 at 9:57pm CST by Ben Levine

Brandon Aiyuk‘s eventual return to the field is starting to come into focus. While the receiver was previously operating without a return timeline as he recovers from a torn ACL and MCL, coach Kyle Shanahan revealed today that Week 6 would be a rough estimate for the receiver’s activation.

“I kind of view all those guys around the same time,” Shanahan said while also referencing injured safety Malik Mustapha and quarterback Kurtis Rourke (via ESPN’s Nick Wagoner). “Whether it’s Mustafa, whether it’s Rourke or whether it’s Brandon. They’re all at different stages, but where they’re at, I always see ’em around Week 6, which means that could be Week 10, it means it could be Week 5, but that’s the area where I start thinking about it, which is a long way away. I know it’s not Week 1 or anything like that, so it’s something I’m not really thinking about too much.”

A Week 6 return would be just short of a year absence for Aiyuk, who suffered his season-ending knee injury in Week 7 of the 2024 campaign. While we’ve seen a number of players return from this injury in less than a calendar year, Wagoner notes that Aiyuk didn’t suffer a “clean” tear. Still, the receiver is expected to make a full recovery.

Aiyuk is currently on the physically unable to perform list and is destined to remain there through the start of the regular season. As Wagoner notes, Aiyuk has been around the squad throughout training camp, with the veteran working with the team’s young wideouts.

Aiyuk’s absence will certainly be felt. Beyond the subtraction of mainstay Deebo Samuel, the 49ers continue to deal with injuries to their WR corps. Jauan Jennings is without a return date as he continues to nurse a calf injury, and Wagoner reported earlier today that fourth-round rookie Jordan Watkins is now sidelined with a high ankle sprain. That injury is expected to sideline the first-year receiver for a month, putting his status for Week 1 in doubt.

As a result, Brock Purdy is eyeing some questionable targets for the start of the regular season. 2024 first-round pick Ricky Pearsall is expected to initially lead the grouping, and the team could also lean on offseason acquisition Demarcus Robinson and 2024 fourth-round pick Jacob Cowing. Otherwise, the rest of the team’s depth consists of the likes of rookie seventh-round pick Junior Bergen, veteran Russell Gage, and former UDFA Terique Owens.

John Lynch: No Return Timetable For 49ers WRs Brandon Aiyuk, Jauan Jennings

August 7th, 2025 at 4:05pm CST by Adam La Rose

The receiver position remains uncertain in the case of the 49ers with Week 1 drawing closer. Both Brandon Aiyuk and Jauan Jennings are sidelined through injury, and in each case there is no firm timeline for a return.

Aiyuk continues to rehab the ACL and MCL tears which ended his 2024 campaign. Throughout the offseason, a main question for San Francisco has been his ability to return to full health in time for the start of the season. Aiyuk has been ahead of schedule, but as of last month a stint on the active/PUP list seemed likely in his case. Such a scenario would ensure at least a four-game absence to begin the campaign.

During a Thursday appearance on KNBR radio, 49ers general manager John Lynch said (via Cam Inman of the San Jose Mercury News) he doubts Aiyuk will be able to play in the team’s regular season opener. He confirmed there is still no timetable in place, though, meaning it remains to be seen is an PUP stint will be deemed necessary. Aiyuk has four years remaining on the $30MM-per-year extension he signed last offseason.

Meanwhile, the 49ers continue to wait for Jennings’ return to action. A calf injury has him sidelined against the backdrop of a request for an upgraded contract. Jennings has not officially asked to be traded, per head coach Kyle Shanahan, but a report from last month stated he will seek a change of scenery in the absence of a raise being worked out through an extension. With nothing imminent on that front, Jennings continues to recover.

“Jauan’s working with our health and performance staff, trying to get back out on the field,” Lynch said of the 28-year-old (via David Bonilla of 49ers WebZone). “Jauan got his calf in the offseason, strained it, and calves can kind of linger, unfortunately. And came out, practiced some, and wasn’t feeling great, and so we’ve kind of put him off to the side… Don’t have any timetable, but we’ll see.”

Jennings enjoyed a career year in 2024 as the 49ers dealt with injuries elsewhere on the receiver depth chart. The decision to trade away Deebo Samuel helped set Jennings up for another season in a large offensive role. One year remains on the former seventh-rounder’s contract and he is owed $4MM for 2025. A strong season would help Jennings’ market for next spring, provided no extension is worked out before that point.

2024 first-rounder Ricky Pearsall is in line to serve as a key figure in San Francisco’s passing attack provided he can remain healthy this season. The team also has veteran Demarcus Robinson and recent signing Robbie Chosen in the mix. Aiyuk and Jennings will each be important elements in the 49ers’ efforts to rebound from last year’s performance, but it is still unclear when either of them will be healthy.

Kyle Shanahan: Jauan Jennings Hasn’t Formally Requested Trade

July 22nd, 2025 at 7:44pm CST by Ben Levine

A report last week indicated that 49ers wide receiver Jauan Jennings either wanted a new contract or a trade. The veteran is still expected to report to training camp tomorrow, and 49ers head coach Kyle Shanahan revealed that his wideout hasn’t formally requested out of San Francisco (per ESPN’s Nick Wagoner).

[RELATED: 49ers WR Jauan Jennings Seeking Extension Or Trade]

Jennings signed a two-year deal last spring that replaced his second-round RFA tender. He proceeded to have a career season as the 49ers navigated a number of injuries. Jennings finished the 2024 campaign with 77 catches for 975 yards and six touchdowns. Set to earn $3.28MM in salary guarantees in 2025 (plus an option bonus of $1.12MM on September 1), the impending free agent is now seeking some long-term security.

With Deebo Samuel no longer on the team and Brandon Aiyuk recovering from a torn ACL, the 49ers are set to be even more dependent on Jennings in 2025. The 49ers front office has dealt with plenty of contract drama at the position in recent years, but Jennings’ lack of track record makes this situation a bit more unique. It remains to be seen if Jennings will carry through with his trade-request threat, and for the time being, it appears both sides will proceed as planned.

If Jennings does suddenly pivot to a holdout or trade request, the 49ers will have to dig even deeper into their depth chart. 2024 first-round pick Ricky Pearsall would likely lead the group, although he’s currently nursing a hamstring issue that landed him on PUP. The team brought in some reinforcement at the position this offseason, signing veterans Demarcus Robinson and Isaiah Hodgins while drafting Jordan Watkins (fourth round) and Junior Bergen (seventh round). The team is also rostering 2024 fourth-round pick Jacob Cowing.

The 49ers could also count on an eventual return for Aiyuk, although it sounds like the star receiver’s comeback is still a ways off. GM John Lynch told reporters today that Aiyuk is still “not anywhere close to having a concrete timeline” (per ESPN’s Adam Schefter). Aiyuk suffered his knee injury in late-October, and it seems like he’s destined to miss at least the first four games of the upcoming campaign.

NFL Minor Transactions: 7/18/25

July 18th, 2025 at 8:31pm CST by Ely Allen

Here are today’s minor NFL transactions as we head into the weekend:

Detroit Lions

Green Bay Packers

San Francisco 49ers

The Lions have added three players to the roster today after a working them out. Bootle has had a cup of coffee with a few teams in the league after going undrafted in 2021. Small didn’t see the field at all as an undrafted rookie with the Titans last year, and Russell becomes the latest undrafted rookie free agent to sign a deal this year. His tenacity has been rewarded two and a half months after the draft.

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