The Titans may begin the season without their first-round pick. They placed Isaiah Wilson on the reserve/COVID-19 list, Field Yates of ESPN.com tweets.

This marks the second time the first-round tackle has landed on the COVID list. Players do not have to test positive to be placed on the list; they can land there if they come in contact with an infected person.

Wilson, a Georgia alum, spent roughly a week on the COVID list earlier this summer. Given Tennessee’s investment, he projects as a player who will at some point become Jack Conklin‘s replacement at right tackle. However, the Titans may not have him to start the season.

In other Titans roster moves, running back Senorise Perry and cornerback Chris Milton will join the team’s 53-man roster. To clear the other roster spot, the Titans placed safety Dane Cruikshank on IR. Players who are carried onto the regular-season roster do not have to miss a full season if placed on IR. This season, players who land on IR can return after three weeks.

Tennessee also set its practice squad Sunday. Trevor Siemian agreed to sign on. The Titans signed the former Broncos starter-turned-journeyman backup late this offseason but did not carry him through to their 53-man roster. He will instead serve as an emergency quarterback of sorts.

Here is the full list:

• OLB Jamal Davis
• TE Tommy Hudson
• OL Brandon Kemp
• K Tucker McCann
• RB Jeremy McNichols
• CB Kareem Orr
• OL David Quessenberry
• OLB Wyatt Ray
• QB Trevor Siemian
• DL Kobe Smith
• CB Tye Smith
• DL Teair Tart
• WR Nick Westbrook-Ikhine