As the 49ers say goodbye to one star, they’ll welcome another. Opening a spot on the 53-man roster by officially placing linebacker Fred Warner on injured reserve, San Francisco will fill it with the activation of tight end George Kittle from IR. Kittle is joined as an IR activation by defensive tackle Kevin Givens.
After suffering a full tear of his right hamstring in a Week 1 win over the Seahawks, Kittle sat out five games – the second-highest total of his career. The six-time Pro Bowler will return to an offense that will go without starting quarterback Brock Purdy for the third straight game. With Purdy dealing with a toe injury, Mac Jones will lead the 4-2 Niners against the 3-2 Falcons on Sunday.
The multi-game absences of Kittle and Purdy have been among several injury-related setbacks for San Francisco’s offense this year. The defense also hasn’t been spared. Star pass rusher Nick Bosa went down with a season-ending ACL tear in Week 3. The unit took a similarly brutal shot when Warner dislocated and fractured his ankle in a loss to the Buccaneers last week. The four-time Pro Bowler underwent surgery and will miss the rest of the regular season. A playoff return for Warner is an extreme long shot.
With Warner out of commission, Tatum Bethune will face a gargantuan task in replacing one of the game’s preeminent defenders. Bethune, a seventh-round pick in 2024, has only made one start in 17 career games. Out of 134 snaps this year, just 48 have come on defense. Bethune has otherwise worked on special teams.
While San Francisco’s defense has lost Warner, it’s getting some D-line depth back with Givens set to make his season debut. Givens hasn’t played in 2025 as a result of a pectoral injury. The seventh-year 49er totaled 3.5 sacks and six QB hits in eight games last season.
In addition to the IR transactions, San Francisco announced that defensive end Trevis Gipson has been signed from the practice squad to the 53-man roster. Joining him for the weekend as standard gameday practice squad elevations will be wide receiver Malik Turner and offensive lineman Nick Zakelj. To make room for Gipson on the active roster, the 49ers waived tight Brayden Willis.
Connor Byrne contributed to this post.